Clinical Trials fMRI

This page lists research, authored by NISOx and NISOx collaborators, concerned with Clinical Trials fMRI.

Publications

• A hybrid procedure for detecting global treatment effects in multivariate clinical trials: theory and applications to fMRI studies
  Giorgos Minas, Fabio Rigat, Thomas E. Nichols, John A.D. Aston, and Nigel Stallard. Statistics in Medicine 31(3): 253–268. doi: 10.1002/sim.4395.
• Validation and pilot application of [ 18F]FDG-PET in evaluation of a metabolic therapy for Alzheimer's disease
  S Tzimopoulou, Vincent Cunningham, Thomas Nichols, Graham Searle, N.P. Bird, Prafull Mistry, et al. Validation and pilot application of [ 18F]FDG-PET in evaluation of a metabolic therapy for Alzheimer's disease: 627-642.
• A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [18F]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate Alzheimer's Disease
  Julian Matthews, Sofia Tzimopoulou, Vincent J Cunningham, Thomas E Nichols, Graham Searle, Nick P Bird, et al. Journal of Alzheimer's Disease 22(4): 1241–1256. 10.3233/JAD-2010-100939.
• Optimizing the Design and Analysis of Clinical Functional Magnetic Resonance Imaging Research Studies
  Cameron S. Carter, Stephan Heckers, Thomas Nichols, Daniel S. Pine, and Stephen Strother. Biological Psychiatry 64(10): 842 - 849. doi: https://doi.org/10.1016/j.biopsych.2008.06.014. Neurodegeneration in Dementia and Depression.